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M Cornebise Selected Research

2- ((1- (3,5- dichlorobenzenesulfonyl)pyrrolidine- 2- carbonyl)amino)- 4- (4- methyl- 2- (methyl- (2- (4- (3- o- tolylureido)phenyl)acetyl)amino)pentanoylamino)butyric acid

2/2005Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
6/2003An assessment of the mechanistic differences between two integrin alpha 4 beta 1 inhibitors, the monoclonal antibody TA-2 and the small molecule BIO5192, in rat experimental autoimmune encephalomyelitis.

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M Cornebise Research Topics

Disease

2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
02/2005 - 06/2003
1Multiple Sclerosis
06/2003

Drug/Important Bio-Agent (IBA)

22- ((1- (3,5- dichlorobenzenesulfonyl)pyrrolidine- 2- carbonyl)amino)- 4- (4- methyl- 2- (methyl- (2- (4- (3- o- tolylureido)phenyl)acetyl)amino)pentanoylamino)butyric acidIBA
02/2005 - 06/2003
1Monoclonal AntibodiesIBA
06/2003
1pyrrolidineIBA
06/2003
1Butyric Acid (Butanoic Acid)IBA
06/2003
1Integrin alpha4beta1 (VLA-4)IBA
06/2003